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Caffeine encapsulated in small unilamellar liposomes: characerization and in vitro release profile
Studies suggest that it enhances the stability of the genome by reducing oxidative damage to DNA
3-7 This translated to improved healing in tendon, ligament, muscle, and even nerve injuries in these rodent models
In the acute phase of ischemia, which is characterized by anoxic depolarization and a massive increase in [Ca 2+ ] i mediated by both Ca 2+ influx and Ca 2+ -induced Ca 2+ release from intracellular stores, the vesicular release from presynaptic terminals further adds to the glutamate elevation
The harmful effect is counteracted by the existence of antioxidant systems, represented by molecules capable of neutralizing ROS, thus preventing the induction of oxidation damage (2,4)
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